Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody.

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Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody.

Recent studies have demonstrated the induced expression of endothelial adhesion molecules including E-selectin (also called endothelial leukocyte adhesion molecule-1), vascular cell adhesion molecule and intercellular adhesion molecule in actively involved mucosa of patients with ulcerative colitis and Crohn's disease. Similar induction has been demonstrated in the colon of the Cotton-top tamar...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1993

ISSN: 0021-9738

DOI: 10.1172/jci116575